Toward identification and characterization of molecular interactions in living cells: Quantifying molecular colocalization in live cell fluorescence microscopy.
A new approach based on bidirectional scanning improves the imaging performance of optoacoustic imaging to quasi-isotropic transverse resolution.
A flexible wide-field endoscope utilising blue excitation light provides label-free contrast of tissue based on fluorescence lifetime imaging of tissue autofluorescence. Fluorescence lifetime imaging (FLIM) of tissue autofluorescence has been shown to provide labelfree contrast between different types and states of tissue. Clinical FLIM can combine lifetime contrast with morphological information to provide a direct […]
Membrane nano-tomography in living cells: Label-free evanescent microscopy enables full-field and real-time tracking of membrane processes.
In vivo and non-invasive: Collagen remodeling after micro-ablative fractional laser resurfacing can be monitored by two-photon microscopy.
Detection of nanoparticles and DNA biomarkers at clinically relevant low levels can be achieved by combining epifluorescent microscopy with dielectrophoretic microarrays.
Monitoring of blood capillary/vessel patterns with spatially resolved diffuse reflectance spectrometry might allow for the early detection of clinical shock.
Raman spectroscopy of the retina coupled with multivariate analysis might become a promising tool to study retina diseases in vivo.
Scientists from NTU have suggested the use of metal-coated microneedles to improve below-skin Raman spectroscopy.
Three-dimensional optoacoustic tomography enables quantitative measurements of nanoparticle concentrations to evaluate their biodistributions in animal models.