Trapping and watching motile cells

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A new approach enables rapid characterization of living suspension cells in 4 dimensions while they are immobilized and manipulated within optical traps.

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Quantifying molecular colocalization in live cell fluorescence microscopy

Toward identification and characterization of molecular interactions in living cells: Quantifying molecular colocalization in live cell fluorescence microscopy.

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Perpendicular geometry for better photoacoustic images

A new approach based on bidirectional scanning improves the imaging performance of optoacoustic imaging to quasi-isotropic transverse resolution.

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New endoscopic technique provides label-free contrast of tissue

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A flexible wide-field endoscope utilising blue excitation light provides label-free contrast of tissue based on fluorescence lifetime imaging of tissue autofluorescence. Fluorescence lifetime imaging (FLIM) of tissue autofluorescence has been shown to provide labelfree contrast between different types and states of tissue. Clinical FLIM can combine lifetime contrast with morphological information to provide a direct […]

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Membranes under observation

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Membrane nano-tomography in living cells: Label-free evanescent microscopy enables full-field and real-time tracking of membrane processes.

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Measuring skin rejuvenation with two-photon microscopy

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In vivo and non-invasive: Collagen remodeling after micro-ablative fractional laser resurfacing can be monitored by two-photon microscopy.

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A synergetic pairing: epifluorescent microscopy and electrophoretic microarrays

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Detection of nanoparticles and DNA biomarkers at clinically relevant low levels can be achieved by combining epifluorescent microscopy with dielectrophoretic microarrays.

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Modeling blood capillaries to prevent shock

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Monitoring of blood capillary/vessel patterns with spatially resolved diffuse reflectance spectrometry might allow for the early detection of clinical shock.

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Monitoring retina inflammation with Raman spectroscopy

Raman spectroscopy of the retina coupled with multivariate analysis might become a promising tool to study retina diseases in vivo.

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SERS probes from silver microneedles get under the skin

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Scientists from NTU have suggested the use of metal-coated microneedles to improve below-skin Raman spectroscopy.

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