Plate reader developed for drug discovery

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A new automated fluorescence lifetime imaging plate reader has been used to study aggregation of HIV-1 Gag proteins.

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Microcarrier Design Strategies for Controlled Bioagent Encapsulation and Release

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Bioactive agents, such as synthetic drugs, proteins, and cells, can be encapsulated in biocompatible microcarriers for a variety of biological applications.

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“Smart” nano-network can control insulin release for diabetes treatment

The nano-network releases insulin in response to changes in blood sugar.

Researchers have developed a network of nanoscale particles that can be injected into the body and release insulin when blood-sugar levels rise.

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Zinc could be a “golden” bullet for bioabsorbable stents

This series of scanning electron microscope images illustrates the corrosion of zinc wire implanted in rats' arteries at 1.5 months, 3 months, 4.5 months and 6 months. The wires degraded at a rate just below 0.2 millimeters per year -- the "magic" value for bioabsorbable stents -- for the first three months. After that, the corrosion accelerated, so the implant would not remain in the artery for too long. Image: Patrick Bowen.

Some materials dissolve too quickly in the body, and some hang around forever — zinc, however, may be just right.

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New materials for heart tissue regeneration

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A new biomaterial for heart tissue regeneration, resembling live cardiac tissue in key characteristics, has been reported.

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New liquid crystal properties could boost self-healing materials

A liquid crystal sample like this one, seen under a microscope, gets tougher when repeatedly compressed, according to research at Rice University. Image: Verduzco Laboratory/Rice University.

Rice University researchers find that silicone liquid crystals stiffen with repeated compression.

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Improving signal-to-noise in biosensing

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Researchers report the application of TRPT and fluorescence lifetime imaging microscopy (FLIM) for heparin sensing and bioimaging.

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Two-photon microscopy dye will reduce cost of characterisation

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New kind of dye could reduce the cost of two-photon microscopy by several orders of magnitude.

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Brush copolymers for gene delivery

Fluorescence images of transfected HeLa cells

Novel pH sensitive brush copolymers with biodegradable polyphosphoester side chains for use as nonviral gene vectors have been developed.

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Magneto-electric nanoparticles deliver anti-HIV drug to the brain

Nanoparticles can cross the blood-brain barrier and send a significantly increased level of AZTTP to HIV-infected cells.

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