New endoscopic technique provides label-free contrast of tissue

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A flexible wide-field endoscope utilising blue excitation light provides label-free contrast of tissue based on fluorescence lifetime imaging of tissue autofluorescence. Fluorescence lifetime imaging (FLIM) of tissue autofluorescence has been shown to provide labelfree contrast between different types and states of tissue. Clinical FLIM can combine lifetime contrast with morphological information to provide a direct […]

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Exploiting surface tension for patterned cell co-cultures

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A simple method for 3D patterning of cell co-cultures has been developed based on capillary forces in a nanostructured microchannel.

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A New Review of Nanocellulose for Biomedical Applications

The image shows an AFM image of cellulose nanocrystals isolated from tunicates (Styela clava).

Dr. Mehdi Jorfi and Prof. E. Johan Foster review the applications of nanocellulose in various biomedical applications.

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Improving nanoparticle cellular uptake

A group at the University of Adelaide have developed an intracellular GSH-responsive drug delivery system with enhanced cellular uptake capability.

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Light-sensitive polymers for controlled gene silencing

New research describes the use of polymers that can bind siRNAs into nanoscale assemblies that do not disassemble until they are irradiated with UV light.

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Controlling cell gene expression with hydrogels

Researchers have developed a hydrogel system containing a spatial gradient of siRNA and studied its effects on encapsulated cells.

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Protein-based bionanomaterial design

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UC Berkeley researchers have published an overview of the use of mammalian elastin, collagen, insect-derived silk and resilin in biomaterials design.

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Targeted killing of tumor cells with cancer nanotherapeutics

Paolo Netti and co-workers have designed and characterized model tumor activated polystyrene nanoparticles (TAP-NPs) that release cytotoxic drugs.

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Better insulin-cell producing transplants

Polymer coating protects pancreatic islet cells by deactivating inflammatory reactive oxygen (ROS) and nitrogen species (RNS).

Researchers develop a nanothin anti-inflammatory polymer material capable of decreasing immune responses involved in insulin-cell transplantation rejection.

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Video abstract: thermogelling polymers in medicine

Dr Loh Xian Jun discusses his review article on potential clinical applications for biodegrable thermogelling polymers.