Novel pH sensitive brush copolymers with biodegradable polyphosphoester side chains for use as nonviral gene vectors have been developed.
Brush copolymers for gene delivery
April 29, 2013 By Leave a Comment
Link to the original paper on Wiley Online Library
Spotlight on Polymer Chemistry Issue 10
April 8, 2013 By Leave a Comment
The Journal of Polymer Science Part A: Polymer Chemistry highlights some important research in the latest issue.
Oxidative damage in DNA-bases – potential for drug design
August 21, 2012 By Leave a Comment
Prof. Mishra’s group at Banaras Hindu University, India has exhaustively studied two specific reactions of hydroxyl and perhydroxyl radicals.
Link to the original paper on Wiley Online Library
Chemical modification of LPEI for gene delivery
August 8, 2012 By Leave a Comment
The PEtOx-b-LPEI copolymer could have important applications in gene delivery and gene silencing as a polymeric vector.
Link to the original paper on Wiley Online Library
Newly modified nanoparticle opens window on future gene editing technologies
June 12, 2012 By Leave a Comment
Researchers at Iowa State University demonstrate the ability to simultaneously deliver proteins and DNA into plant cells.
Link to the original paper on Wiley Online Library
Click Chemistry for Gene Therapy
January 17, 2011 By Leave a Comment
A reducibly-degradable hyperbranched polymer PEI-SS-HP composed of LMW PEI via a disulfide-containing linkage is demonstrated as a promising gene vector.
Link to the original paper on Wiley Online Library
